Cell-permeable. Kartogenin promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes (EC?? = 100 nM). Displays chondroprotective effects in vitro and is efficacious in two animal models of osteoarthritis.
Additional Information
Product #
K-2559
CAS #
4727-31-5
MW
317.342
Appearance
Powder
Storage Temp
Room Temp
Therapeutic Area
Musculoskeletal Disorders
Use
Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes in osteoarthritis