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A potent, cell-permeable reversible, and selective inhibitor of EGF receptor (EGFR)tyrosine kinase activity (IC=0.45 nM). The reversible nature of this compound makes it a less effective antitumor agent than PD 168393

Additional Information

Synonyms	4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline
Product #	P-1647
CAS #	216163-53-0
Chemical Name	4-[(3-Bromophenyl)amino]-6-propionylamidoquinazoline
Formula	C17H15BrN4O
MW	371.2
Appearance	Yellow Solid
Purity	98%
Solubility	Soluble in DMSO
Storage Temp	-20°C
Use	PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR?

Additional Information

MDL Number	MFCD02179208
ChemACX	X4983431-3
InChI	InChI=1S/C17H15BrN4O/c1-2-16(23)21-13-6-7-15-14(9-13)17(20-10-19-15)22-12-5-3-4-11(18)8-12/h3-10H,2H2,1H3,(H,21,23)(H,19,20,22)
SMILES	CCC(=O)Nc1ccc2c(c1)c(ncn2)Nc3cccc(c3)Br