*Please inquire the availability for this product. Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research suggests that the gilvocarcins act as photoactivated cross-linkers of DNA to histones.
Additional Information
Synonyms
Anandimycin A, Toromycin, 1072B
Product #
G-2519
CAS #
77879-90-4
Formula
C27H26O9
MW
494.5
Appearance
Yellow crystals
Purity
>95% by HPLC
Solubility
Soluble in DMSO, DMF (moderately), methanol (moderately), ethanol (moderately), and water (poor)
Melting Point
322.54 °C
Storage Temp
-20°C
Therapeutic Area
Oncological Disorders
Use
A metabolite that displays potent antibacterial, antifungal and antiviral activity