六月丁香激情,丁香在线综合,5个男人躁我一个爽视频

您好，歡迎來到拜力生物網(wǎng)站！請登錄注冊

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時間：08:30-17:30

主營產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁 > 產(chǎn)品中心 > AGScientific > AGScientific產(chǎn)品

Dorsomorphin Inhibit Myostatin / GDF8 Signaling, inhibits Bmp-Smad pathway

訂購信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Dorsomorphin Inhibit Myostatin / GDF8 Signaling, inhibits Bmp-Smad pathway

品牌：AG Scientific

貨號：

規(guī)格：5 mg

貨期：

應(yīng)用：

咨詢客服

立即購買加入購物車

CAS:866405-64-3Formula:C24H25N5OMW:399.5Appearance:YellowSolidPurity:>98%(TLC)

商品詳情參考文獻(xiàn) 相關(guān)資料

Cell-permeable. A potent, selective, reversible and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki=109 nM in the presence of ATP and no AMP). Displays no significant inhibition of JAK3, PKA, PKCθ, SYK and ZAPK. Suppresses food intake in mice and inhibits the effects of AICAR and metformin.Also inhibits bone morphogenic protein (BMP) type I receptors (ALK2, ALK3 and ALK6). Promotes cardiomyogenesis in mouse embryonic stem cells. In addition, recently Dorsomorphin has shown to induce protective autophagy in cancer cells through AMPK inhibition-independent pathway.

Additional Information

Synonyms	BML-275; Compound C; AMPK INHIBITOR
Product #	D-1310
CAS #	866405-64-3
Chemical Name	6-[4-(2-Piperidin-1-yl)-ethoxy)- phenyl)]-3-pyridin-4-yl- pyrazolo[1,5-a]-pyrimidine
Formula	C₂₄H₂₅N₅O
MW	399.5
Appearance	Yellow Solid
Purity	>98%(TLC)
Solubility	May be dissolved in DMSO (4 mg/ml, warm).
Melting Point	244.93 °C
Storage Temp	Store desiccated at -20°C. Store solutions at -20°C for up to 3 months
Therapeutic Area	Neurological Disorders
Use	A potent inhibitor of AMPK

Additional Information

MDL Number	MFCD08705402
ChemACX	X1561649-0
InChI	InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2
SMILES	C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3

熱銷產(chǎn)品