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A necroptosis inhibitor. The biological activity of necrostatin-7 (Nec 7) is different from that of necrostatin 1 to necrostatin 5 as Nec 7 does not inhibit RIP1 kinase. Nec-7 may target an additional regulatory molecule in the pathway.

Additional Information

Synonyms	NEC-7, Necroptosis inhibitor 7
Product #	N-1225
CAS #	351062-08-3
Chemical Name	(Z)-5-((4-Fluorophenyl)-1H-pyazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one
Formula	C16H10N5OS2F
MW	371.41
Appearance	Yellow Solid
Purity	98% by NMR
Solubility	Soluble in DMSO or EtOH.
Storage Temp	-20°C

Additional Information

MDL Number	MFCD02334728
InChI	InChI=1S/C16H10FN5OS2/c17-11-3-1-9(2-4-11)13-10(8-20-21-13)7-12-14(23)22(15(18)25-12)16-19-5-6-24-16/h1-8,18H,(H,20,21)/b12-7+,18-15?
SMILES	c1cc(ccc1c2c(c[nH]n2)/C=C/3C(=O)N(C(=N)S3)c4nccs4)F