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Pimozide

品牌：AG Scientific

貨號：

規(guī)格：50 mg

貨期：

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CAS:2062-78-4Formula:C28H29F2N3OMW:461.55Appearance:WhiteSolidPurity:98%byTLC

商品詳情參考文獻相關(guān)資料

Cell-permeable. An antipsychotic drug and D2 dopamine receptor antagonist; binds with high affinity to the cloned 5-HT7 receptor. A Stat5 inhibitor; decreases Stat5 tyrosine phosphorylation, but does not affect Bcr-Abl or other tyrosine kinases.

Additional Information

Synonyms	1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Product #	P-2397
CAS #	2062-78-4
Chemical Name	1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
Formula	C₂₈H₂₉F₂N₃O
MW	461.55
Appearance	White Solid
Purity	98% by TLC
Solubility	DMSO (100 mM)
Melting Point	214-218 °C
Storage Temp	2-8°C
Therapeutic Area	Psychological Disorders
Use	Pimozide is a D2DR inhibitor and antipsychotic which binds with very high affinity and inhibits SR-7

Additional Information

MDL Number	MFCD00055081
ChemACX	X1004358-8
InChI	InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)
SMILES	c1ccc2c(c1)[nH]c(=O)n2C3CCN(CC3)CCCC(c4ccc(cc4)F)c5ccc(cc5)F

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