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Griseofulvin

品牌：AG Scientific

貨號：

規(guī)格：25 mg

貨期：

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CAS:126-07-8Formula:C17H17CIO6MW:352.1Appearance:Whitesolid.Purity:>99%byHPLC

商品詳情參考文獻(xiàn) 相關(guān)資料

Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect to the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.

Additional Information

Synonyms	Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533
Product #	G-1243
CAS #	126-07-8
Formula	C₁₇H₁₇CIO₆
MW	352.1
Appearance	White solid.
Purity	>99% by HPLC
Solubility	Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Melting Point	218-220 °C
Storage Temp	-20°C
Therapeutic Area	Infectious Diseases
Use	Griseofulvin is an antifungal drug. It is used both in animals and humans, to treat fungal infections of the skin

Additional Information

MDL Number	MFCD00082343
InChI	InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
SMILES	C[C@@H]1CC(=O)C=C([C@]12C(=O)c3c(cc(c(c3O2)Cl)OC)OC)OC

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