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Cell-permeable. A naturally occurring anthraquinone that displays a range of biological activities including anti-inflammatory, anti-tumor and neuroprotective effects. Acts as a potent p56lck tyrosine kinase inhibitor (IC= 18.5 M).

Additional Information

Synonyms	1,3,8-Trihydroxy-6-methylanthracene-9,10-dione
Product #	E-2305
CAS #	518-82-1
Chemical Name	1,3,8-Trihydroxy-6-methylanthracene-9,10-dione
Formula	C15H10O5
MW	270.24
Appearance	Yellow Solid
Purity	98% by HPLC
Solubility	DMSO (50 mM) or aqueous alkali
Melting Point	256-257 °C
Storage Temp	-20°C
Therapeutic Area	Oncological Disorders
Use	A potent p56lck tyrosine kinase inhibitor shown to suppress HER2/neu tyrosine kinase activity in breast cancer cells

Additional Information

MDL Number	MFCD00001207
ChemACX	X1009707-1
InChI	InChI=1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
SMILES	Cc1cc2c(c(c1)O)C(=O)c3c(cc(cc3O)O)C2=O