三级二级一区AV三区,成人啪啪一区二区三区

您好，歡迎來(lái)到拜力生物網(wǎng)站！請(qǐng)登錄注冊(cè)

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時(shí)間：08:30-17:30

主營(yíng)產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測(cè)溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁(yè) 產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁(yè) > 產(chǎn)品中心 > Xcessbio > Xcessbio產(chǎn)品

1-methyl-D-tryptophan(D-1MT),IDOInhibitor

訂購(gòu)信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

1-methyl-D-tryptophan(D-1MT),IDOInhibitor

品牌：Xcessbio

貨號(hào)：M60291-2s

規(guī)格：2 mg solid

貨期：

應(yīng)用：

咨詢客服

立即購(gòu)買加入購(gòu)物車

1-methyl-D-tryptophan(D-1MT),IDOInhibitor

商品詳情參考文獻(xiàn) 相關(guān)資料

Product Information

Molecular Weight:	218.25
Formula:	C₁₂H₁₄N₂O₂
Purity:	≥98%
CAS#:	110117-83-4
Solubility:	Water up to 5 mM (warming)
Chemical Name:	1-methyl-D-tryptophan
Storage:	Powder: 4^oC 1 year. DMSO: 4^oC 3 month; -20^oC 1 year.

Biological Activity:

1-methyl-D-tryptophan (D-1MT) is a potent and selective indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 ~7 μM. It disrupts tryptophan catabolism and enhances the antitumor and antiviral immunoresponses of CD8+ T-cells in vitro. It can reduce tumor volume in mice with xenografts overexpressing IDO.

How to Use:

In vitro: D-1MT was used at 10-50 μM final concentration in various in vitro assays.
In vivo: D-1MT was dosed at 5 mg/Kg orally to mice bearing A20 B-cell lymphoma.

Reference:

1. Rytelewski M, et al. Suppression of immunodominant antitumor and antiviral CD8+ T cell responses by indoleamine 2,3-dioxygenase. (2014) PLoS One. 9(2):e90439.?
2. Nakamura N, et al. Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice. (2015) Int J Hematol. 102(3):327-34.?

? ? ??

Products are for research use only. Not for human use.?

熱銷產(chǎn)品