間充質(zhì)干細(xì)胞是特征明確的一類**干細(xì)胞。它們有發(fā)育為成熟細(xì)胞的潛在能力而產(chǎn)生脂肪、軟骨、骨骼和肌肉。這些特性與它們發(fā)育中的可塑性共同作用，使人們對(duì)用間充質(zhì)干細(xì)胞來替換受損組織的潛在能力產(chǎn)生了極大的興趣。分離于臍帶膠樣組織（wharton’s jelly）中的間充質(zhì)干細(xì)胞，在體外含有sonic hedgehog和FGF-8的神經(jīng)元培養(yǎng)基中將轉(zhuǎn)換為神經(jīng)細(xì)胞和神經(jīng)膠質(zhì)。間充質(zhì)干細(xì)胞也可以轉(zhuǎn)化成脂肪細(xì)胞和成骨細(xì)胞。此外，在適于心肌細(xì)胞生長(zhǎng)的培養(yǎng)基中，它們有潛能分化成心肌細(xì)胞。間充質(zhì)干細(xì)胞表達(dá)基質(zhì)受體CD44和CD105，以及間充質(zhì)干細(xì)胞標(biāo)志物SH2和SH3，但不表達(dá)造血系統(tǒng)標(biāo)志物CD34。
Sciencell研究實(shí)驗(yàn)室的人臍帶間充質(zhì)干細(xì)胞是從人臍帶膠樣組織（wharton’s jelly）中分離得到的，原代凍存，冰凍運(yùn)輸。每管細(xì)胞密度*過5×10^5/ml。人臍帶間充質(zhì)干細(xì)胞經(jīng)免疫熒光鑒定、和CD73，CD90，CD105的抗體鑒定，以及分化后的脂質(zhì)染色鑒定。本細(xì)胞經(jīng)檢測(cè)不含HIV-1、HBV、HCV、支原體、細(xì)菌、酵母菌和真菌。如采用ScienCell 實(shí)驗(yàn)室特制的培養(yǎng)基，可保證此細(xì)胞15倍增增殖。
推薦培養(yǎng)基：間充質(zhì)干細(xì)胞培養(yǎng)基 (MSCM, Cat. #7501)
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貨號(hào)
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7530
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產(chǎn)地
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美國(guó)
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縮寫
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HUMSC
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規(guī)格
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5 x 10^5 /1ml
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用途
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科研
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儲(chǔ)存
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液氮
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運(yùn)輸
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干冰
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