乳腺上皮細(xì)胞（HMEpiC）位于乳腺小葉的泡狀腺，配合乳腺管和脂肪組織，形成一個(gè)復(fù)雜的乳腺系統(tǒng)。MEpiC受各種生長(zhǎng)因子和激素信號(hào)影響，并在產(chǎn)前產(chǎn)后、青春期、孕期經(jīng)歷生長(zhǎng)、侵襲和分化等過程。激素分泌、細(xì)胞外基質(zhì)成分異常和其他遺傳因素會(huì)引起MEpiC的增殖失控，導(dǎo)致乳腺癌的發(fā)展。了解MEpiC的特性將有助于我們研究乳腺癌疾病的發(fā)病機(jī)理和新的治療靶標(biāo)。
ScienCell實(shí)驗(yàn)室的HMEpiC分離自人乳腺，原代凍存，冰凍運(yùn)輸。每管細(xì)胞密度*過5×10^5/ml。細(xì)胞經(jīng)Cyt-14,-18,-19的免疫熒光鑒定。本細(xì)胞經(jīng)檢測(cè)不含HIV-1、HBV、HCV、支原體、細(xì)菌、酵母菌和真菌。如采用ScienCell 實(shí)驗(yàn)室特制的培養(yǎng)基，可保證此細(xì)胞15次或以上的倍增。
推薦培養(yǎng)基：乳腺上皮細(xì)胞培養(yǎng)基 (MEpiCM, Cat. #7611)
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貨號(hào)
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7610
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產(chǎn)地
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美國(guó)
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縮寫
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HMEpiC
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規(guī)格
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5 x 10^5 /1ml
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用途
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科研
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儲(chǔ)存
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液氮
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運(yùn)輸
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干冰
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1.) Zhang L, Webster TJ. (2013) "Effects of chemically modified nanostructured PLGA on functioning of lung and breast cancer cells." Int J Nanomedicine. 8: 1907-19.
2.) Lu RM, Chen MS, Chang DK, Chiu CY, Lin WC, Yan SL, Wang YP, Kuo YS, Yeh CY, Lo A, Wu HC. (2013) "Targeted drug delivery systems mediated by a novel Peptide in breast cancer therapy and imaging." PLoS One. 8: e66128.
3.) Fong C, Weerawardena A, Sagnella SM, Mulet X, Krodkiewska I, Chong J, Drummond CJ. (2011) "Monodisperse Nonionic Isoprenoid-Type Hexahydrofarnesyl Ethylene Oxide Surfactants: High Throughput Lyotropic Liquid Crystalline Phase Determination." Langmuir.
4.) Gong X, Moghaddam MJ, Sagnella SM, Conn CE, Danon SJ, Waddington LJ, Drummond CJ. (2011) "Lamellar crystalline self-assembly behaviour and solid lipid nanoparticles of a palmityl prodrug analogue of Capecitabine-A chemotherapy agent." Colloids Surf B Biointerfaces. 85: 349-59.
5.) Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng CW, Hwang D, Martin-Montalvo A, Saavedra J, Ingles S, de Cabo R, Cohen P, Longo VD. (2011) "Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans." Sci Transl Med. 3: 70ra13.
6.) Sagnella SM, Conn CE, Krodkiewska I, Moghaddam M, Drummond CJ. (2010) "Endogenous nonionic saturated monoethanolamide lipids: solid state, lyotropic liquid crystalline, and solid lipid nanoparticle dispersion behavior." J Phys Chem B. 114: 1729-37.
7.) Huang Y, Song N, Ding Y, Yuan S, Li X, Cai H, Shi H, Luo Y. (2009) "Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis." Cancer Res. 69: 7529-37.
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