血管內(nèi)皮細(xì)胞主要作用是維持血管的動(dòng)態(tài)平衡。此細(xì)胞能合成和分泌凝血和纖溶系統(tǒng)中的活化和抑制因子，同時(shí)也能合成和分泌影響著血小板粘附和聚集的某些介質(zhì)。內(nèi)皮細(xì)胞還可以釋放具有調(diào)控細(xì)胞增殖和血管壁張力功能的分子。人肺動(dòng)脈內(nèi)皮細(xì)胞上的腺苷受體被脂多糖激活后，會(huì)引起參與急性肺損傷的病生理過(guò)程的IL-6的釋放。許多此類(lèi)以及其他的作用過(guò)程可以應(yīng)用培養(yǎng)的細(xì)胞在體外研究進(jìn)行研究，人肺動(dòng)脈內(nèi)皮細(xì)胞正是這類(lèi)研究中普遍應(yīng)用的細(xì)胞類(lèi)型。
人肺動(dòng)脈內(nèi)皮細(xì)胞提取于人肺組織，**代培養(yǎng)末期凍存。每管含有細(xì)胞數(shù)>5×105 cells/ml，此細(xì)胞通過(guò)vWF/Factor VIII 和CD31 (P-CAM)免疫熒光染色驗(yàn)證，經(jīng)測(cè)試不含有HIV-1、 HBV、HCV、支原體、細(xì)菌、酵母和真菌。細(xì)胞可以達(dá)到15倍增。
推薦培養(yǎng)基：內(nèi)皮細(xì)胞培養(yǎng)基 (ECM, Cat. #1001)
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貨號(hào)
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3100
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產(chǎn)地
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美國(guó)
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縮寫(xiě)
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HPAEC
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規(guī)格
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5 x 10^5 /1ml
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用途
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科研
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儲(chǔ)存
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液氮
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運(yùn)輸
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干冰
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