亚洲AV 日韩国产有码,麻多视频豆传媒

您好，歡迎來(lái)到拜力生物網(wǎng)站！請(qǐng)登錄注冊(cè)

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時(shí)間：08:30-17:30

主營(yíng)產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測(cè)溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁(yè) 產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁(yè) > 產(chǎn)品中心 > Antibodies > Antibodies產(chǎn)品

訂購(gòu)信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-FBXO11 Antibody

品牌：Antibodies

貨號(hào)：

規(guī)格：100μl

貨期：

應(yīng)用：

咨詢客服

立即購(gòu)買(mǎi) 加入購(gòu)物車(chē)

Anti-FBXO11 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-FBXO11 Antibody See all FBXO11 primary antibodies
Description:	Rabbit polyclonal antibody to FBXO11
Specificity:	The antibody detects endogenous level of total FBXO11 antibody.
Applications:	WB, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human FBXO11.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were purified by affinity purification using immunogen.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DTL/CDT2, BCL6 and PRDM1/BLIMP1. The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6, thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells. The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL, an important step for the regulation of TGF-beta signaling, cell migration and the timing of the cell-cycle progression and exit. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53.
Tissue Specificity:	Isoform 5 is expressed in keratinocytes, fibroblasts and melanocytes.
Cellular Location:	Nucleus. Chromosome.
Database Links:	Entrez Gene: 80204?Human Entrez Gene: 225055?Mouse Entrez Gene: 301674?Rat Omim: 607871?Human SwissProt: Q86XK2?Human SwissProt: Q7TPD1?Mouse SwissProt: Q7TSL3?Rat Unigene: 352677?Human Unigene: 386857?Mouse Unigene: 36585?Rat
Synonyms:	F box only protein 11 Antibody F box protein 11 Antibody F-box only protein 11 Antibody FBX11 Antibody FBX11_HUMAN Antibody FBXO11 Antibody PRMT9 Antibody Protein arginine N methyltransferase 9 Antibody Ubiquitin protein ligase E3 component n recognin 6 Antibody UBR6 Antibody UG063H01 Antibody VIT 1 Antibody VIT-1 Antibody VIT1 Antibody Vitiligo associated protein 1 Antibody Vitiligo associated protein VIT 1 Antibody Vitiligo-associated protein 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.