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Anti-Factor IX Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-Factor IX Antibody

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Overview

Name:	Anti-Factor IX Antibody See all Factor IX primary antibodies
Description:	Rabbit polyclonal antibody to Factor IX
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Recombinant protein fragment contain a sequence corresponding to a region within amino acids 217 and 423 of Human F9
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Purified by antigen-affinity chromatography.
Formulation:	Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:	Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.

Target

Function:	Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
Tissue Specificity:	Detected in blood plasma (at protein level) (PubMed:3857619, PubMed:8295821, PubMed:2592373, PubMed:9169594, PubMed:19846852). Synthesized primarily in the liver and secreted in plasma.
Involvement in Disease:	Hemophilia B: An X-linked blood coagulation disorder characterized by a permanent tendency to hemorrhage, due to factor IX deficiency. It is phenotypically similar to hemophilia A, but patients present with fewer symptoms. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Thrombophilia, X-linked, due to factor IX defect: A hemostatic disorder characterized by a tendency to thrombosis.
Sequence Similarities:	Belongs to the peptidase S1 family.
Post-Translational Modification:	Activated by factor XIa, which excises the activation peptide (PubMed:9169594, PubMed:1730085). The propeptide can also be removed by snake venom protease (PubMed:20004170, PubMed:20080729).
Cellular Location:	Secreted.
Database Links:	Entrez Gene: 2158?Human Omim: 300746?Human SwissProt: P00740?Human Unigene: 522798?Human
Synonyms:	Cf-9 Antibody Cf9 Antibody Christmas Disease Antibody Christmas factor Antibody Coagulant factor IX Antibody Coagulation factor 9 Antibody Coagulation factor IX Antibody Coagulation factor IXa heavy chain Antibody F9 Antibody F9 p22 Antibody FA9_HUMAN Antibody Factor 9 Antibody Factor IX Antibody Factor IX Deficiency Antibody Factor IX F9 Antibody FactorIX Antibody FIX Antibody FIX F9 Antibody Haemophilia B Antibody HEMB Antibody MGC129641 Antibody MGC129642 Antibody P19 Antibody Plasma thromboplastic component Antibody Plasma Thromboplastin Component Antibody PTC Antibody THPH8 Antibody
Information:	Target information shown above is from the UniProt Consortium.