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Anti-ETS1 (A32) Antibody

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Anti-ETS1 (A32) Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-ETS1 (A32) Antibody See all ETS1 primary antibodies
Description:	Rabbit polyclonal antibody to ETS1 (A32)
Specificity:	ETS1 (A32) pAb detects endogenous levels of ETS1 protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to the N-terminus of Human ETS1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 52 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Target

Function:	Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.
Tissue Specificity:	Highly expressed within lymphoid cells. Isoforms c-ETS-1A and Ets-1 p27 are both detected in all fetal tissues tested, but vary with tissue type in ***** tissues. None is detected in brain or kidney.
Sequence Similarities:	Belongs to the ETS family.
Post-Translational Modification:	Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2; which inhibits transcriptional activity.
Cellular Location:	Cytoplasm. Nucleus. Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.
Database Links:	Entrez Gene: 2113?Human Entrez Gene: 23871?Mouse Entrez Gene: 24356?Rat Omim: 164720?Human SwissProt: P14921?Human SwissProt: P27577?Mouse SwissProt: P41156?Rat Unigene: 369438?Human Unigene: 292415?Mouse Unigene: 88756?Rat
Synonyms:	Avian erythroblastosis virus E26 (v ets) oncogene homolog 1 Antibody C ets 1 protein Antibody c-ets-1 Antibody ETS 1 Antibody Ets protein Antibody ETS proto-oncogene 1, transcription factor Antibody ETS1 Antibody ETS1 oncogene Antibody ETS1 protein Antibody ETS1_HUMAN Antibody EWSR 2 Antibody EWSR2 Antibody FLJ10768 Antibody Oncogene ETS1 Antibody P54 Antibody Protein C-ets-1 Antibody v ets avian erythroblastosis virus E2 oncogene homolog Antibody v ets avian erythroblastosis virus E2 oncogene homolog 1 Antibody v ets avian erythroblastosis virus E26 oncogene homolog 1 Antibody v ets erythroblastosis virus E26 oncogene homolog 1 Antibody v-ets erythroblastosis virus E26 oncogene homolog 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.