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Anti-Ephrin-B1 / 2 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-Ephrin-B1 / 2 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-Ephrin-B1 / 2 Antibody See all Ephrin-B1 primary antibodies
Description:	Rabbit polyclonal antibody to Ephrin-B1 / 2
Specificity:	Ephrin-B1 / 2 Polyclonal Antibody detects endogenous levels of Ephrin-B1 / 2 protein.
Applications:	WB, IHC, ELISA
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from human Ephrin-B1 / 2 around the non-phosphorylation site of Y330.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20?C / 1 year

Target

Function:	Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
Tissue Specificity:	Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas.
Involvement in Disease:	Craniofrontonasal syndrome: X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies.
Sequence Similarities:	Belongs to the ephrin family.
Post-Translational Modification:	Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 1947?Human Entrez Gene: 13641?Mouse Entrez Gene: 25186?Rat Omim: 300035?Human SwissProt: P98172?Human SwissProt: P52795?Mouse SwissProt: P52796?Rat Unigene: 144700?Human Unigene: 3374?Mouse Unigene: 44398?Rat
Synonyms:	CFND Antibody CFNS Antibody Craniofrontonasal syndrome (craniofrontonasal dysplasia) Antibody EFL 3 Antibody EFL-3 Antibody EFL3 Antibody EFNB1 Antibody EFNB1_HUMAN Antibody Elk L Antibody ELK ligand Antibody ELK-L Antibody Eph related receptor tyrosine kinase ligand 2 Antibody EPH-related receptor tyrosine kinase ligand 2 Antibody Ephrin B1 Antibody Ephrin-B1 Antibody EPLG2 Antibody LERK 2 Antibody LERK-2 Antibody LERK2 Antibody Ligand of eph related kinase 2 Antibody MGC8782 Antibody
Information:	Target information shown above is from the UniProt Consortium.