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Anti-ENC1 Antibody

品牌：Antibodies

貨號：

規(guī)格：100μg

貨期：

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Anti-ENC1 Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-ENC1 Antibody See all ENC1 primary antibodies
Description:	Goat polyclonal antibody to ENC1.
Applications:	ELISA, WB, IHC
Reactivity:	Rat, Human
Immunogen:	Synthetic peptide corresponding to Human ENC1 (internal region).
Sequence:	TSVSHDKLPKVQC
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism.
Tissue Specificity:	Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in *** brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in *** pancreas. May be down-regulated in neuroblastoma tumors.
Post-Translational Modification:	Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination.
Cellular Location:	Nucleus matrix. Cytoplasm. Cytoplasm > Cytoskeleton.
Database Links:	Entrez Gene: 8507?Human Entrez Gene: 294674?Rat Omim: 605173?Human SwissProt: O14682?Human Unigene: 104925?Human Unigene: 3039?Rat
Synonyms:	CCL 28 Antibody CCL28 Antibody Ectoderm neural cortex protein 1 Antibody Ectoderm-neural cortex protein 1 Antibody Ectodermal neural cortex (with BTB like domain) Antibody ENC 1 Antibody ENC-1 Antibody ENC1 Antibody ENC1_HUMAN Antibody FLJ39259 Antibody Kelch like 35 Antibody Kelch like 37 Antibody Kelch-like protein 37 Antibody KLHL 35 Antibody KLHL35 Antibody KLHL37 Antibody NRPB Antibody Nuclear matrix protein NRP/B Antibody Nuclear restricted protein BTB domain like (brain) Antibody OTTHUMP00000128235 Antibody OTTHUMP00000222054 Antibody p53 induced gene 10 protein Antibody p53-induced gene 10 protein Antibody PIG 10 Antibody PIG10 Antibody TP53I10 Antibody Tumor protein p53 inducible protein 10 Antibody
Information:	Target information shown above is from the UniProt Consortium.