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Anti-EF-1 α1 / 2 (Acetyl-Lys41) Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

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Anti-EF-1 α1 / 2 (Acetyl-Lys41) Antibody

商品詳情參考文獻相關(guān)資料

Name:	Anti-EF-1 α1 / 2 (Acetyl-Lys41) Antibody See all EF-1 α1 primary antibodies
Description:	Rabbit polyclonal antibody to EF-1 α1 / 2 (Acetyl-Lys41)
Specificity:	Acetyl-EF-1 α1 / 2 (K41) Polyclonal Antibody detects endogenous levels of EF-1 α1 / 2 protein only when acetylated at K41.
Applications:	WB, ELISA
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from the human EF-1 α1 / 2 around the acetylation site of K41.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20?C / 1 year

Function:	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Tissue Specificity:	Brain, placenta, lung, liver, kidney, pancreas but barely detectable in heart and skeletal muscle.
Sequence Similarities:	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
Post-Translational Modification:	ISGylated.
Cellular Location:	Cytoplasm. Nucleus. Nucleus > Nucleolus. Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens.