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Anti-DYX1C1 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-DYX1C1 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-DYX1C1 Antibody See all DYX1C1 primary antibodies
Description:	Goat polyclonal antibody to DYX1C1.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human DYX1C1 (N terminal).
Sequence:	PLQVSDYSWQQTKT-C
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility.
Tissue Specificity:	Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells.
Involvement in Disease:	Dyslexia 1: A relatively common, complex cognitive disorder characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities. It is a multifactorial trait, with evidence for familial clustering and heritability. Ciliary dyskinesia, primary, 25: A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Patients may exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome.
Cellular Location:	Nucleus. Cytoplasm.
Database Links:	Entrez Gene: 161582?Human Omim: 608706?Human SwissProt: Q8WXU2?Human Unigene: 126403?Human
Synonyms:	Dyslexia susceptibility 1 candidate 1 Antibody Dyslexia susceptibility 1 candidate gene 1 protein Antibody DYX1 Antibody DYX1C1 Antibody DYXC1 Antibody DYXC1_HUMAN Antibody EKN1 Antibody FLJ37882 Antibody MGC70618 Antibody RD Antibody
Information:	Target information shown above is from the UniProt Consortium.