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Anti-DRD5 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-DRD5 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-DRD5 Antibody See all DRD5 primary antibodies
Description:	Rabbit polyclonal antibody to DRD5.
Applications:	WB, IHC, IF
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human DRD5.
Protein Length:	477
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Tissue Specificity:	Neuron-specific, localized primarily within limbic regions of the brain.
Involvement in Disease:	Benign essential blepharospasm: A primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness.
Sequence Similarities:	Belongs to the G-protein coupled receptor 1 family.
Cellular Location:	Cell membrane.
Database Links:	Entrez Gene: 1816?Human Entrez Gene: 13492?Mouse Entrez Gene: 25195?Rat Omim: 126453?Human SwissProt: P21918?Human SwissProt: Q8BLD9?Mouse SwissProt: P25115?Rat Unigene: 380681?Human Unigene: 167154?Mouse Unigene: 138110?Rat
Synonyms:	D(1B) dopamine receptor Antibody D(5) dopamine receptor Antibody D1 beta dopamine receptor Antibody D1B dopamine receptor Antibody D1beta dopamine receptor Antibody D5 dopamine receptor Antibody DBDR Antibody Dopamine D5 receptor Antibody Dopamine receptor D1B Antibody Dopamine Receptor D5 Antibody DRD 1B Antibody DRD 5 Antibody DRD1B Antibody DRD1L2 Antibody DRD5 Antibody DRD5_HUMAN Antibody MGC10601 Antibody
Information:	Target information shown above is from the UniProt Consortium.