It has no cross responses to DAP or ZIP kinases. The approximately 70 kDa band is probably non-related to DRAK2 although it is peptide blockable.
Applications:
E, WB, ICC
Reactivity:
Human
Immunogen:
Raised against a peptide corresponding to amino acids 351 to 365 of human DRAK2.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Ion exchange chromatography purified
Formulation:
Supplied in PBS containing 0.02% sodium azide.
Storage:
Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
Function:
Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.
Tissue Specificity:
Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
Sequence Similarities:
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.