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Anti-DR4 Antibody

品牌：Antibodies

貨號(hào)：

規(guī)格：100μl

貨期：

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Anti-DR4 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Name:	Anti-DR4 Antibody See all DR4 primary antibodies
Description:	Rabbit polyclonal antibody to DR4
Applications:	E, WB, ICC
Reactivity:	Human
Immunogen:	Raised against a peptide corresponding to amino acids near the carboxy terminus of human DR4 protein.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	DEAE purified
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Function:	Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Tissue Specificity:	Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 8797?Human Omim: 603611?Human SwissProt: O00220?Human Unigene: 213467?Human Unigene: 591834?Human
Synonyms:	Apo2 Antibody CD261 Antibody Cytotoxic TRAIL receptor Antibody Death receptor 4 Antibody DR4 Antibody NF related apoptosis-inducing ligand receptor 1 Antibody TNF receptor superfamily member 10a Antibody TNF-related apoptosis-inducing ligand receptor 1 Antibody TNFRSF10A Antibody TR10A_HUMAN Antibody TRAIL receptor 1 Antibody TRAIL-R1 Antibody TRAILR 1 Antibody TRAILR1 Antibody Tumor necrosis factor receptor superfamily member 10A Antibody Tumor necrosis factor receptor superfamily member 10a variant 2 Antibody Tumor necrosis factor receptor superfamily, member 10a Antibody
Information:	Target information shown above is from the UniProt Consortium.