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Anti-DR1 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-DR1 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-DR1 Antibody See all DR1 primary antibodies
Description:	Rabbit polyclonal antibody to DR1.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human DR1.
Protein Length:	176
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Sequence Similarities:	Belongs to the NC2 beta/DR1 family.
Post-Translational Modification:	Phosphorylation regulates its interaction with TBP. Not phosphorylated when bound to DRAP1.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 1810?Human Entrez Gene: 13486?Mouse Entrez Gene: 289881?Rat Omim: 601482?Human SwissProt: Q01658?Human SwissProt: Q91WV0?Mouse SwissProt: Q5XI68?Rat Unigene: 348418?Human Unigene: 303534?Mouse Unigene: 6666?Rat
Synonyms:	Down regulator of transcription 1 Antibody Down regulator of transcription 1 TBP binding Antibody Down-regulator of transcription 1 Antibody down-regulator of transcription 1, TBP-binding (negative cofactor 2) Antibody DR 1 Antibody DR1 Antibody Dr1 protein Antibody NC 2 Antibody NC2 Antibody NC2 beta Antibody NC2-beta Antibody NC2B_HUMAN Antibody Negative co factor 2 Antibody Negative cofactor 2 Antibody Negative cofactor 2 beta Antibody Negative cofactor 2-beta Antibody Protein Dr1 Antibody TATA binding protein associated phosphoprotein Antibody TATA box/binding protein associated phosphoprotein DR1 Antibody TATA-binding protein-associated phosphoprotein Antibody
Information:	Target information shown above is from the UniProt Consortium.