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Anti-DOK6 Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

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Anti-DOK6 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Name:	Anti-DOK6 Antibody See all DOK6 primary antibodies
Description:	Rabbit polyclonal antibody to DOK6
Specificity:	The antibody detects endogenous levels of total DOK6 protein.
Applications:	WB, IF
Reactivity:	Human, Mouse
Immunogen:	Synthesized peptide derived from internal of human DOK6.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Function:	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.
Tissue Specificity:	Highly expressed in fetal and ***** brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis.
Sequence Similarities:	Belongs to the DOK family. Type B subfamily.
Post-Translational Modification:	On Ret activation, phosphorylated on one or more C-terminal tyrosine residues by an Src family kinase.
Database Links:	Entrez Gene: 220164?Human Entrez Gene: 623279?Mouse Omim: 611402?Human SwissProt: Q6PKX4?Human SwissProt: Q2MHE5?Mouse
Synonyms:	Docking protein 5 Antibody Docking protein 5 like Antibody Docking protein 6 Antibody DOK 6 Antibody DOK5 Antibody DOK5L Antibody DOK6 Antibody Downstream of tyrosine kinase 6 Antibody HsT3226 Antibody MGC20785 Antibody Protein dok 5 Antibody
Information:	Target information shown above is from the UniProt Consortium.