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Anti-DOK3 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-DOK3 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Name:	Anti-DOK3 Antibody See all DOK3 primary antibodies
Description:	Rabbit polyclonal antibody to DOK3
Specificity:	The antibody detects endogenous level of total DOK3 protein.
Applications:	E, WB, IHC
Dilutions:	ELISA: 1:1000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:10-1:50
Reactivity:	Human
Immunogen:	Fusion protein corresponding to C terminal 300 amino acids of human docking protein 3
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Predicted MW:	53kd
Formulation:	Supplied at 1mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Storage:	Store at -20?C / 1 year

Function:	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity).
Tissue Specificity:	Expressed in spleen.
Sequence Similarities:	Belongs to the DOK family. Type A subfamily.
Post-Translational Modification:	Constitutively tyrosine-phosphorylated.
Cellular Location:	Cytoplasm. Cell membrane.
Database Links:	Entrez Gene: 79930?Human Omim: 611435?Human SwissProt: Q7L591?Human Unigene: 720849?Human
Synonyms:	Docking protein 3 Antibody DOK 3 Antibody DOK Like Protein Antibody DOK3 Antibody DOK3_HUMAN Antibody DOKL Pending Antibody Downstream of tyrosine kinase 3 Antibody p62 DOK Like Protein Antibody
Information:	Target information shown above is from the UniProt Consortium.