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Anti-DEFA1 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-DEFA1 Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-DEFA1 Antibody See all DEFA1 primary antibodies
Description:	Rabbit polyclonal antibody to DEFA1
Specificity:	The antibody detects endogenous level of total DEFA1 protein.
Applications:	E, WB, IHC
Dilutions:	ELISA: 1:500-1:5000 Western blotting: 1:500-1:1000 Immunohistochemistry: 1:25-1:50
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to a region derived from 49-63 amino acids of Human Defensin, alpha 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Predicted MW:	10kd
Formulation:	Supplied at 1.1mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Storage:	Store at -20?C / 1 year

Target

Background:

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

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