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Anti-Cystatin B (N84) Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-Cystatin B (N84) Antibody

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Name:	Anti-Cystatin B (N84) Antibody See all Cystatin B primary antibodies
Description:	Rabbit polyclonal antibody to Cystatin B (N84)
Specificity:	Cystatin B (N84) pAb detects endogenous levels of Cystatin B protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 51-100 of Human Cystatin B.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 11 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Function:	This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
Involvement in Disease:	Epilepsy, progressive myoclonic 1: An autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures. The onset, occurring between 6 and 13 years of age, is characterized by convulsions. Myoclonus begins 1 to 5 years later. The twitchings occur predominantly in the proximal muscles of the extremities and are bilaterally symmetrical, although asynchronous. At first small, they become late in the clinical course so violent that the victim is thrown to the floor. Mental deterioration and eventually dementia develop.
Sequence Similarities:	Belongs to the cystatin family.
Cellular Location:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 1476?Human Entrez Gene: 13014?Mouse Entrez Gene: 25308?Rat Omim: 601145?Human SwissProt: P04080?Human SwissProt: Q62426?Mouse SwissProt: P01041?Rat Unigene: 695?Human Unigene: 6095?Mouse Unigene: 1233?Rat
Synonyms:	CHROW21 Antibody CPI B Antibody CPI-B Antibody CST 6 Antibody CST6 Antibody CSTB Antibody Cystatin B Antibody Cystatin B (stefin B) Antibody Cystatin-B Antibody CYTB Antibody CYTB_HUMAN Antibody EPM1 Antibody EPM1A Antibody Liver thiol proteinase inhibitor Antibody PME Antibody Stefin B Antibody Stefin-B Antibody STF B Antibody STFB Antibody ULD Antibody
Information:	Target information shown above is from the UniProt Consortium.