The antibody detects endogenous levels of total CYP2B6 protein.
Applications:
WB, IHC
Reactivity:
Human
Immunogen:
Synthetic peptide corresponding to a region derived from internal residues of human cytochrome P450, family 2, subfamily B, polypeptide 6
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Antigen affinity purification.
Concentration:
2.9mg / ml
Formulation:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:
Store at -20?C
Target
Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase.
Tissue Specificity:
Expressed in liver, lung and heart right ventricle.
Sequence Similarities:
Belongs to the cytochrome P450 family.
Post-Translational Modification:
Phosphorylation is accompanied by a decrease in enzyme activity.