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Anti-CYP26B1 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-CYP26B1 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CYP26B1 Antibody See all CYP26B1 primary antibodies
Description:	Goat polyclonal antibody to CYP26B1.
Applications:	ELISA, IHC
Reactivity:	Human, Mouse
Immunogen:	Synthetic peptide corresponding to Human CYP26B1 (internal region).
Sequence:	C-SQARSEDKDGRFH
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Essential for postnatal survival. Plays a central role in germ cell development: acts by degrading RA in the developing testis, preventing STRA8 expression, thereby leading to delay of meiosis. Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells, inducing arrest in G0 phase of the cell cycle and preventing meiotic entry. Plays a role in skeletal development, both at the level of patterning and in the ossification of bone and the establishment of some synovial joints.
Sequence Similarities:	Belongs to the cytochrome P450 family.
Cellular Location:	Endoplasmic reticulum membrane. Microsome membrane.
Database Links:	Entrez Gene: 56603?Human Entrez Gene: 232174?Mouse Omim: 605207?Human SwissProt: Q9NR63?Human SwissProt: Q811W2?Mouse Unigene: 91546?Human Unigene: 255246?Mouse
Synonyms:	CP26 Antibody CP26B_HUMAN Antibody CYP26A2 Antibody cyp26b1 Antibody Cytochrome P450 26A2 Antibody Cytochrome P450 26B Antibody Cytochrome P450 26B1 Antibody Cytochrome P450 family 26 subfamily B polypeptide 1 Antibody Cytochrome P450 retinoic acid-inactivating 2 Antibody Cytochrome P450 retinoid metabolizing protein Antibody Cytochrome P450 subfamily XXVIA, polypeptide 2 Antibody Cytochrome P450 subfamily XXVIB polypeptide 1 Antibody Cytochrome P450RAI-2 Antibody DKFZp686G0638 Antibody dol Antibody EC 1.14. Antibody fc21d03 Antibody MGC129613 Antibody P450 26A2 Antibody P450 retinoic acid inactivating 2 Antibody P450RAI 2 Antibody P450RAI2 Antibody Retinoic acid metabolizing cytochrome Antibody Retinoic acid-metabolizing cytochrome Antibody RHFCA Antibody stocksteif Antibody wu:fc21d03 Antibody wu:fc26h10 Antibody zgc:76999 Antibody
Information:	Target information shown above is from the UniProt Consortium.