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Anti-CTDSP1 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-CTDSP1 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CTDSP1 Antibody See all CTDSP1 primary antibodies
Description:	Rabbit polyclonal antibody to CTDSP1
Specificity:	The antibody detects endogenous levels of total CTDSP1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthesized peptide derived from N-terminal of human CTDSP1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Tissue Specificity:	Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
Cellular Location:	Nucleus. Colocalizes with RNA polymerase II.
Database Links:	Entrez Gene: 58190?Human Omim: 605323?Human SwissProt: Q9GZU7?Human Unigene: 444468?Human
Synonyms:	Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 Antibody Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Antibody CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1 Antibody CTD small phosphatase 1 Antibody CTDS1_HUMAN Antibody CTDSP1 Antibody NIF3 Antibody NLI IF Antibody NLI interacting factor 3 Antibody NLI-IF Antibody NLI-interacting factor 3 Antibody NLIIF Antibody Nuclear LIM interactor interacting factor 3 Antibody Nuclear LIM interactor-interacting factor 3 Antibody SCP1 Antibody Small C-terminal domain phosphatase 1 Antibody Small CTD phosphatase 1 Antibody
Information:	Target information shown above is from the UniProt Consortium.