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Anti-CtBP1 (Ab-422) Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-CtBP1 (Ab-422) Antibody

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Name:	Anti-CtBP1 (Ab-422) Antibody See all CtBP1 primary antibodies
Description:	Rabbit polyclonal antibody to CtBP1 (Ab-422)
Specificity:	The antibody detects endogenous levels of total CtBP1 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthesized non-phosphopeptide derived from human CtBP1 around the phosphorylation site of serine 422 (A-P-S(p)-P-G).
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Function:	Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Tissue Specificity:	Expressed in germinal center B-cells.
Sequence Similarities:	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Post-Translational Modification:	The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.
Cellular Location:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 1487?Human Omim: 602618?Human SwissProt: Q13363?Human Unigene: 208597?Human Unigene: 594321?Human
Synonyms:	BARS Antibody brefeldin A- ribosylated substrate Antibody C terminal binding protein 1 Antibody C-terminal-binding protein 1 Antibody CTBP Antibody CtBP1 Antibody CTBP1_HUMAN Antibody MGC104684 Antibody
Information:	Target information shown above is from the UniProt Consortium.