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Anti-CSNK1E Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-CSNK1E Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CSNK1E Antibody See all CSNK1E primary antibodies
Description:	Rabbit polyclonal antibody to CSNK1E
Specificity:	The antibody detects endogenous level of total CSNK1E antibody.
Applications:	WB, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human CSNK1E.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were purified by affinity purification using immunogen.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
Tissue Specificity:	Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
Sequence Similarities:	Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Post-Translational Modification:	Autophosphorylated. Partially dephosphorylated by PPP5C. May be dephosphorylated by PP1.
Cellular Location:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 1454?Human Entrez Gene: 27373?Mouse Entrez Gene: 58822?Rat Omim: 600863?Human SwissProt: P49674?Human SwissProt: Q9JMK2?Mouse Unigene: 474833?Human Unigene: 30199?Mouse Unigene: 203721?Rat
Synonyms:	Casein kinase 1 epsilon Antibody Casein kinase I Antibody Casein kinase I epsilon Antibody Casein kinase I isoform epsilon Antibody CK1 epsilon Antibody CKI epsilon Antibody CKI-epsilon Antibody CKIe Antibody CKIepsilon Antibody CSNK 1E Antibody CSNK1E Antibody DBT Antibody Doubletime, Drosophila, homolog of Antibody EC 2.7.11.1 Antibody epsilon isoform Antibody HCK IE Antibody KC1E Antibody KC1E_HUMAN Antibody kinase CK1 epsilon Antibody MGC 10398 Antibody
Information:	Target information shown above is from the UniProt Consortium.