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Anti-CREBZF Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-CREBZF Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CREBZF Antibody See all CREBZF primary antibodies
Description:	Rabbit polyclonal antibody to CREBZF
Specificity:	The antibody detects endogenous levels of total CREBZF protein.
Applications:	WB, IF
Reactivity:	Human, Mouse
Immunogen:	Synthesized peptide derived from internal of human CREBZF.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Tissue Specificity:	In *****s, expressed most abundantly in heart, liver and skeletal muscle, moderately abundant in kidney and pancreas, and barely detectable in lung. In fetal tissues, expressed most abundantly in kidney and very low amounts in heart, lung and liver.
Sequence Similarities:	Belongs to the bZIP family. ATF subfamily.
Cellular Location:	Nucleus. Colocalizes in promyelocytic leukemia protein nuclear bodies (PML-NB) with CREB3 and HCFC1.
Database Links:	Entrez Gene: 58487?Human Entrez Gene: 233490?Mouse Omim: 606444?Human SwissProt: Q9NS37?Human SwissProt: Q91ZR3?Mouse Unigene: 535319?Human Unigene: 714910?Human Unigene: 29496?Mouse
Synonyms:	1110034C16Rik Antibody 6330417B10Rik Antibody AI225749 Antibody AI606244 Antibody CREB/ATF bZIP transcription factor Antibody Crebzf Antibody FLJ94018 Antibody HCF-binding transcription factor Zhangfei Antibody Host cell factor-binding transcription factor Zhangfei Antibody LAZip Antibody LAZipII Antibody SHP-interacting leucine zipper protein Antibody SMILE Antibody ZF Antibody Zhangfei Antibody ZHANG_HUMAN Antibody
Information:	Target information shown above is from the UniProt Consortium.