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Anti-COL4A3BP Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-COL4A3BP Antibody

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Overview

Name:	Anti-COL4A3BP Antibody See all COL4A3BP primary antibodies
Description:	Goat polyclonal antibody to COL4A3BP.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human COL4A3BP (internal region).
Sequence:	C-KREDSWQKRLDKETEK
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
Tissue Specificity:	Widely expressed.
Involvement in Disease:	Mental retardation, autosomal dominant 34: A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.
Post-Translational Modification:	Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity. Inactivated by hyperphosphorylation of serine residues by CSNK1G2/CK1 that triggers dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.
Cellular Location:	Cytoplasm. Golgi apparatus. Endoplasmic reticulum. Preferentially localized to the Golgi apparatus.
Database Links:	Entrez Gene: 10087?Human Omim: 604677?Human SwissProt: Q9Y5P4?Human Unigene: 270437?Human
Synonyms:	Alpha 3 type IV collagen binding protein Antibody C43BP_HUMAN Antibody Ceramide transfer protein Antibody Ceramide transporter Antibody CERT Antibody Cert protein Antibody CERTL Antibody COL4A3BP Antibody Collagen type IV alpha 3 (Goodpasture antigen) binding protein Antibody Collagen type IV alpha 3 binding protein Antibody Collagen type IV alpha-3-binding protein Antibody FLJ20597 Antibody Goodpasture antigen binding protein Antibody Goodpasture antigen-binding protein Antibody GPBP Antibody hCERT Antibody Lipid transfer protein CERTL Antibody Procollagen type IV alpha 3 (Goodpasture antigen) binding protein Antibody StAR related lipid transfer (START) domain containing 11 Antibody StAR related lipid transfer protein 11 Antibody StAR-related lipid transfer protein 11 Antibody StARD 11 Antibody StARD11 Antibody START domain containing 11 Antibody START domain containing protein 11 Antibody START domain-containing protein 11 Antibody
Information:	Target information shown above is from the UniProt Consortium.