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Anti-CLCA4 Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-CLCA4 Antibody

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Name:	Anti-CLCA4 Antibody See all CLCA4 primary antibodies
Description:	Rabbit polyclonal antibody to CLCA4
Specificity:	The antibody detects endogenous levels of total CLCA4 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human Calcium-activated chloride channel regulator 4
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	0.4mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Function:	May be involved in mediating calcium-activated chloride conductance.
Tissue Specificity:	Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp.
Sequence Similarities:	Belongs to the CLCR family.
Post-Translational Modification:	The translation product is autoproteolytically cleaved by the metalloprotease domain in the endoplasmic reticulum into a N-terminal and a C-terminal products that remain physically associated with each other. The cleavage is necessary for calcium-activated chloride channel (CaCC) activation activity.
Cellular Location:	Cell membrane. Apical cell membrane. Secreted. The C-terminus 30 kDa form is anchored to the membrane. The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus.
Database Links:	Entrez Gene: 22802?Human SwissProt: Q14CN2?Human Unigene: 567422?Human
Synonyms:	30 kDa form Antibody CaCC-2 Antibody Calcium-activated chloride channel family member 4 Antibody Calcium-activated chloride channel protein 2 Antibody Calcium-activated chloride channel regulator 4 Antibody CLCA4 Antibody CLCA4_HUMAN Antibody hCaCC-2 Antibody hCLCA4 Antibody
Information:	Target information shown above is from the UniProt Consortium.