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Anti-CHRNA4 Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-CHRNA4 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CHRNA4 Antibody See all CHRNA4 primary antibodies
Description:	Rabbit polyclonal antibody to CHRNA4
Specificity:	The antibody detects endogenous levels of total CHRNA4 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human cholinergic receptor, nicotinic, alpha 4 (neuronal)
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1.2mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.
Involvement in Disease:	Epilepsy, nocturnal frontal lobe, 1: An autosomal dominant focal epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
Sequence Similarities:	Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-4/CHRNA4 sub-subfamily.
Cellular Location:	Cell junction > Synapse > Postsynaptic cell membrane. Cell membrane. Cell membrane.
Database Links:	Entrez Gene: 1137?Human Omim: 118504?Human SwissProt: P43681?Human Unigene: 10734?Human
Synonyms:	A4 nicotinic receptor Antibody Acetylcholine receptor alpha 4 neural Antibody Acetylcholine receptor neuronal nicotinic alpha 4 subunit Antibody ACH 4 Antibody ACH4 Antibody ACHA4_HUMAN Antibody AChR Antibody Acra 4 Antibody Acra4 Antibody Alpha4 nAChR Antibody BFNC Antibody Cholinergic receptor nicotinic alpha 4 Antibody Cholinergic receptor nicotinic alpha polypeptide 4 Antibody CHRNA 4 Antibody CHRNA4 Antibody EBN Antibody EBN 1 Antibody EBN1 Antibody NACHR Antibody NACRA 4 Antibody NACRA4 Antibody Neuronal acetylcholine receptor subunit alpha-4 Antibody Neuronal nicotinic acetylcholine receptor alpha 4 subunit Antibody Nicotinic Acetylcholine Receptor alpha 4 Antibody
Information:	Target information shown above is from the UniProt Consortium.