欧美大片18禁AAA免费视频,欧美一区二区三区久久综合

您好，歡迎來(lái)到拜力生物網(wǎng)站！請(qǐng)登錄注冊(cè)

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時(shí)間：08:30-17:30

主營(yíng)產(chǎn)品： ELISA試劑盒、抗體、補(bǔ)體血清、兔補(bǔ)體、干擾素、小鼠測(cè)溫儀、進(jìn)口試劑、Quidel代理、Swant代理、PBL Assay Science代理

網(wǎng)站首頁(yè) 產(chǎn)品中心代理品牌新聞資訊資源中心關(guān)于我們

所在位置：首頁(yè) > 產(chǎn)品中心 > Antibodies > Antibodies產(chǎn)品

訂購(gòu)信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-CFTR Antibody

品牌：Antibodies

貨號(hào)：

規(guī)格：50μl

貨期：

應(yīng)用：

咨詢客服

立即購(gòu)買(mǎi) 加入購(gòu)物車(chē)

Anti-CFTR Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CFTR Antibody See all CFTR primary antibodies
Description:	Rabbit polyclonal antibody to CFTR
Specificity:	CFTR Polyclonal Antibody detects endogenous levels of CFTR protein.
Applications:	WB, IHC, ELISA
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from human CFTR around the non-phosphorylation site of S737.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1mg / ml
Formulation:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:	Store at -20?C / 1 year

Target

Function:	Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.
Tissue Specificity:	Expressed in the respiratory airway, including bronchial epithelium, and in the female reproductive tract, including oviduct (at protein level).
Involvement in Disease:	Cystic fibrosis: A common generalized disorder of the exocrine glands which impairs clearance of secretions in a variety of organs. It is characterized by the triad of chronic bronchopulmonary disease (with recurrent respiratory infections), pancreatic insufficiency (which leads to malabsorption and growth retardation) and elevated sweat electrolytes. It is the most common genetic disease in Caucasians, with a prevalence of about 1 in 2'000 live births. Inheritance is autosomal recessive. Congenital bilateral absence of the vas deferens: Important cause of sterility in men and could represent an incomplete form of cystic fibrosis, as the majority of men suffering from cystic fibrosis lack the vas deferens.
Sequence Similarities:	Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
Post-Translational Modification:	Phosphorylated; activates the channel. It is not clear whether PKC phosphorylation itself activates the channel or permits activation by phosphorylation at PKA sites. Phosphorylated by AMPK.
Cellular Location:	Early endosome membrane. Cell membrane. In the oviduct and bronchus, detected on the apical side of epithelial cells, but not associated with cilia.
Database Links:	Entrez Gene: 1080?Human Entrez Gene: 12638?Mouse Entrez Gene: 24255?Rat Omim: 602421?Human SwissProt: P13569?Human SwissProt: P26361?Mouse SwissProt: P34158?Rat Unigene: 489786?Human Unigene: 621460?Human Unigene: 661104?Human Unigene: 15621?Mouse Unigene: 124539?Rat
Synonyms:	ABC 35 Antibody ABC35 Antibody ABCC 7 Antibody ABCC7 Antibody ATP binding cassette sub family C member 7 Antibody ATP Binding Cassette Superfamily C Member 7 Antibody ATP binding cassette transporter sub family C member 7 Antibody ATP-binding cassette sub-family C member 7 Antibody cAMP dependent chloride channel Antibody cAMP-dependent chloride channel Antibody CF Antibody CFTR Antibody CFTR/MRP Antibody CFTR_HUMAN Antibody Channel conductance controlling ATPase Antibody Channel conductance-controlling ATPase Antibody Cystic fibrosis transmembrane conductance regulator Antibody Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C, member 7) Antibody Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7 Antibody Cystic Fibrosis Transmembrane Regulator Antibody dJ760C5.1 Antibody MRP 7 Antibody MRP7 Antibody TNR CFTR Antibody
Information:	Target information shown above is from the UniProt Consortium.