The antibody detects endogenous levels of total CERS1 protein.
Applications:
IHC
Reactivity:
Human
Immunogen:
Synthetic peptide corresponding to residues near the C terminal of human ceramide synthase 1
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Antigen affinity purification.
Concentration:
1.4mg / ml
Formulation:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:
Store at -20?C
Target
Function:
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (By similarity).
Involvement in Disease:
Epilepsy, progressive myoclonic 8: A severe form of progressive myoclonic epilepsy characterized by myoclonus, generalized tonic-clonic seizures and moderate to severe cognitive impairment.
Cellular Location:
Endoplasmic reticulum membrane.
Database Links:
Entrez Gene: 10715?Human
Omim: 606919?Human
SwissProt: P27544?Human
Unigene: 412355?Human
Synonyms:
Ceramide synthase 1 Antibody
CerS1 Antibody
CERS1_HUMAN Antibody
LAG1 Antibody
LAG1 homolog ceramide synthase 1 Antibody
LAG1 longevity assurance homolog 1 Antibody
LASS 1 Antibody
LASS1 Antibody
Longevity assurance (LAG1 S. cerevisiae) homolog 1 Antibody
Longevity assurance gene 1 Antibody
Longevity assurance gene 1 protein homolog 1 Antibody
MGC90349 Antibody
Protein LAG1 Antibody
Protein UOG 1 Antibody
Protein UOG-1 Antibody
UOG 1 protein Antibody
UOG1 Antibody
Upstream of GDF1 Antibody
Information:
Target information shown above is from the UniProt Consortium.