The mouse monoclonal antibody 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.
Applications:
FC, IP, WB, IHC-Fr, ICC
Reactivity:
Human, Non-Human Primates, Porcine, Dog
Immunogen:
HEL erythroleukemia cells.
Host:
Mouse
Clonality:
Monoclonal
Clone:
5E10
Isotype:
IgG1
Conjugate:
FITC
Product Form:
Liquid
Formulation:
Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
Storage:
Store in the dark at 2-8°C. Avoid prolonged exposure to light.
Target
Introduction:
CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.