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Anti-CD86 Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-CD86 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CD86 Antibody See all CD86 primary antibodies
Description:	Rabbit polyclonal antibody to CD86
Specificity:	The antibody detects endogenous level of total CD86 protein.
Applications:	WB, IHC, IF, IP
Reactivity:	Human
Immunogen:	Recombinant protein of human CD86.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were purified by affinity purification using immunogen.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Tissue Specificity:	Expressed by activated B-lymphocytes and monocytes.
Post-Translational Modification:	Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation.
Cellular Location:	Cell membrane.
Database Links:	Entrez Gene: 942?Human Omim: 601020?Human SwissProt: P42081?Human Unigene: 171182?Human
Synonyms:	Activation B7-2 antigen Antibody Activation B7-2 antigen 3 Antibody B-lymphocyte activation antigen B7-2 Antibody B-lymphocyte activation antigen B7-2 2 Antibody B7 Antibody B7 2 Antibody B7-2 Antibody B7.2 Antibody B70 Antibody B72 antigen Antibody BU63 Antibody CD28 antigen ligand 2 Antibody CD28 antigen ligand 2 2 Antibody Cd28l2 Antibody CD28LG2 Antibody CD86 Antibody CD86 antigen Antibody CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) Antibody CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 Antibody CD86 molecule Antibody CD86_HUMAN Antibody CLS1 Antibody CTLA-4 counter-receptor B7.2 Antibody CTLA-4 counter-receptor B7.2 2, 3 Antibody Early T-cell costimulatory molecule 1 Antibody ETC-1 Antibody FUN 1 Antibody FUN-1 Antibody LAB72 Antibody Ly-58 Antibody Ly58 Antibody MB7 Antibody MB7-2 Antibody Membrane glycoprotein Antibody MGC34413 Antibody T-lymphocyte activation antigen CD86 Antibody TS/A-2 Antibody
Information:	Target information shown above is from the UniProt Consortium.