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Anti-CD86 Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

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Anti-CD86 Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-CD86 Antibody See all CD86 primary antibodies
Description:	Rabbit polyclonal antibody to CD86.
Applications:	WB, IHC, ICC, IF, IP
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, ICC: 1:50 - 1:100, IF: 1:50 - 1:100, IP: 1:50 - 1:100.
Reactivity:	Human, Mouse
Immunogen:	Recombinant protein of human CD86.
Protein Length:	329
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Tissue Specificity:	Expressed by activated B-lymphocytes and monocytes.
Post-Translational Modification:	Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation.
Cellular Location:	Cell membrane.
Database Links:	Entrez Gene: 942?Human Entrez Gene: 12524?Mouse Omim: 601020?Human SwissProt: P42081?Human SwissProt: P42082?Mouse Unigene: 171182?Human Unigene: 1452?Mouse
Synonyms:	Activation B7-2 antigen Antibody Activation B7-2 antigen 3 Antibody B-lymphocyte activation antigen B7-2 Antibody B-lymphocyte activation antigen B7-2 2 Antibody B7 Antibody B7 2 Antibody B7-2 Antibody B7.2 Antibody B70 Antibody B72 antigen Antibody BU63 Antibody CD28 antigen ligand 2 Antibody CD28 antigen ligand 2 2 Antibody Cd28l2 Antibody CD28LG2 Antibody CD86 Antibody CD86 antigen Antibody CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) Antibody CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2 Antibody CD86 molecule Antibody CD86_HUMAN Antibody CLS1 Antibody CTLA-4 counter-receptor B7.2 Antibody CTLA-4 counter-receptor B7.2 2, 3 Antibody Early T-cell costimulatory molecule 1 Antibody ETC-1 Antibody FUN 1 Antibody FUN-1 Antibody LAB72 Antibody Ly-58 Antibody Ly58 Antibody MB7 Antibody MB7-2 Antibody Membrane glycoprotein Antibody MGC34413 Antibody T-lymphocyte activation antigen CD86 Antibody TS/A-2 Antibody
Information:	Target information shown above is from the UniProt Consortium.