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Anti-CD200R1 Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-CD200R1 Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-CD200R1 Antibody See all CD200R1 primary antibodies
Description:	Rabbit polyclonal antibody to CD200R1
Specificity:	The antibody detects endogenous levels of total CD200R1 protein.
Applications:	IHC
Reactivity:	Human
Immunogen:	Fusion protein corresponding to a region derived from internal residues of human CD200 receptor 1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	3mg / ml
Formulation:	Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:	Store at -20?C

Target

Function:	Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
Tissue Specificity:	Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells.
Sequence Similarities:	Belongs to the CD200R family.
Post-Translational Modification:	The mature form of isoform 2 and/or isoform 4 starts at sequence position 27 of the corresponding isoform.
Cellular Location:	Cell membrane.
Database Links:	Entrez Gene: 131450?Human Omim: 607546?Human SwissProt: Q8TD46?Human Unigene: 309158?Human
Synonyms:	CD 200R Antibody CD200 cell surface glycoprotein receptor Antibody CD200 receptor 1 Antibody CD200R Antibody Cd200r1 Antibody Cell surface glycoprotein CD200 receptor 1 Antibody Cell surface glycoprotein OX2 receptor Antibody Cell surface glycoprotein OX2 receptor 1 Antibody cell surface glycoprotein receptor CD200 Antibody CRTR 2 Antibody CRTR2 Antibody HCRTR2 Antibody MO2R1_HUMAN Antibody MOX2 receptor Antibody MOX2R Antibody OX2R Antibody
Information:	Target information shown above is from the UniProt Consortium.