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Anti-CCNH Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-CCNH Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CCNH Antibody See all CCNH primary antibodies
Description:	Rabbit polyclonal antibody to CCNH
Specificity:	The antibody detects endogenous level of total CCNH protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human CCNH.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were purified by affinity purification using immunogen.
Concentration:	1.0mg / ml
Formulation:	Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C

Target

Function:	Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Sequence Similarities:	Belongs to the cyclin family. Cyclin C subfamily.
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 902?Human Entrez Gene: 66671?Mouse Entrez Gene: 84389?Rat Omim: 601953?Human SwissProt: P51946?Human SwissProt: Q61458?Mouse SwissProt: Q9R1A0?Rat Unigene: 292524?Human Unigene: 18474?Mouse Unigene: 23255?Rat
Synonyms:	6330408H09Rik Antibody AI661354 Antibody AV102684 Antibody AW538719 Antibody CAK Antibody CAK complex subunit Antibody ccnh Antibody CCNH_HUMAN Antibody CDK activating kinase Antibody CDK activating kinase complex subunit Antibody Cyclin dependent kinase activating kinase Antibody cyclin dependent kinase activating kinase complex subunit Antibody Cyclin H Antibody Cyclin-H Antibody CyclinH Antibody MO15 associated protein Antibody MO15-associated protein Antibody p34 Antibody p36 Antibody p37 Antibody
Information:	Target information shown above is from the UniProt Consortium.