Synthetic peptide corresponding to Human CCKAR (internal region).
Sequence:
C-FEASQKKSAKERKPST
Host:
Goat
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:
100 μg at 0.5 mg/ml.
Product Form:
Liquid
Formulation:
Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
Function:
Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Tissue Specificity:
Pancreas and brain. Also expressed in the gastrointestinal system and vagus nerve.
Sequence Similarities:
Belongs to the G-protein coupled receptor 1 family.
Cellular Location:
Cell membrane.
Database Links:
Entrez Gene: 886?Human
Entrez Gene: 24889?Rat
Omim: 118444?Human
SwissProt: P32238?Human
SwissProt: P30551?Rat
Unigene: 129?Human
Unigene: 10184?Rat
Synonyms:
CCK A Antibody
CCK A receptor Antibody
CCK AR Antibody
CCK-A receptor Antibody
CCK1 R Antibody
CCK1-R Antibody
CCK1R Antibody
CCKA Antibody
CCKA receptor Antibody
CCKAR Antibody
CCKR Type A Antibody
CCKRA Antibody
Cholecystokinin 1 receptor Antibody
Cholecystokinin A receptor Antibody
Cholecystokinin receptor type A Antibody
Cholecystokinin type A receptor Antibody
Information:
Target information shown above is from the UniProt Consortium.