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Anti-Casein Kinase 1 Alpha Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

應用：

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Anti-Casein Kinase 1 Alpha Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-Casein Kinase 1 Alpha Antibody See all Casein Kinase 1 Alpha primary antibodies
Description:	Chicken polyclonal antibody to Casein Kinase 1 Alpha.
Applications:	WB, ICC/IF, ABC, IHC
Dilutions:	WB: 1:10,000. IF: 1:500-1:1000. ABC: 1:5,000.
Reactivity:	Human, Horse, Cow, Porcine, Chicken, Rat, Mouse
Immunogen:	Recombinant full length CK1a (shortest isoform).
Host:	Chicken
Clonality:	Polyclonal
Isotype:	IgY
Conjugate:	Unconjugated
Purity:	IgY preparation.
Product Form:	Liquid
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (By similarity).
Sequence Similarities:	Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Cellular Location:	Cytoplasm. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Chromosome > Centromere > Kinetochore. Nucleus speckle. Cytoplasm > Cytoskeleton > Cilium basal body. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton.
Database Links:	Entrez Gene: 1452?Human Entrez Gene: 93687?Mouse Entrez Gene: 113927?Rat Omim: 600505?Human SwissProt: P48729?Human SwissProt: Q8BK63?Mouse SwissProt: P97633?Rat Unigene: 529862?Human Unigene: 712555?Human Unigene: 26908?Mouse Unigene: 472989?Mouse Unigene: 473442?Mouse Unigene: 23810?Rat
Synonyms:	Casein Kinase 1 alpha Antibody Casein kinase 1 alpha 1 Antibody Casein kinase I isoform alpha Antibody CK1 Antibody CK1A Antibody CKI alpha Antibody CKI-alpha Antibody CKIa Antibody Clock regulator kinase Antibody Csnk1a1 Antibody Down regulated in lung cancer Antibody HLCDGP1 Antibody KC1A_HUMAN Antibody PRO2975 Antibody
Information:	Target information shown above is from the UniProt Consortium.