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Anti-CACNB4 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-CACNB4 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-CACNB4 Antibody See all CACNB4 primary antibodies
Description:	Goat polyclonal antibody to CACNB4.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human CACNB4 (internal region).
Sequence:	C-DYPDSYQDTYKPH
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Tissue Specificity:	Expressed predominantly in the cerebellum and kidney.
Involvement in Disease:	Epilepsy, idiopathic generalized 9: A disorder characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain. Juvenile myoclonic epilepsy 6: A subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue. Episodic ataxia 5: A disorder characterized by episodes of vertigo and ataxia that last for several hours. Interictal examination show spontaneous downbeat and gaze-evoked nystagmus, mild dysarthria and truncal ataxia.
Sequence Similarities:	Belongs to the calcium channel beta subunit family.
Database Links:	Entrez Gene: 785?Human Omim: 601949?Human SwissProt: O00305?Human Unigene: 120725?Human
Synonyms:	CAB4 Antibody CACB4_HUMAN Antibody CACNB4 Antibody CACNLB4 Antibody Calcium channel voltage dependent beta 4 subunit Antibody Calcium channel voltage dependent subunit beta 4 Antibody Calcium channel voltage-dependent subunit beta 4 Antibody Dihydropyridine sensitive L type calcium channel beta 4 subunit Antibody EA5 Antibody EIG9 Antibody EJM Antibody EJM4 Antibody EJM6 Antibody Voltage-dependent L-type calcium channel subunit beta-4 Antibody
Information:	Target information shown above is from the UniProt Consortium.