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Anti-C1D Antibody

品牌：Antibodies

貨號(hào)：

規(guī)格：100μg

貨期：

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Anti-C1D Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-C1D Antibody See all C1D primary antibodies
Description:	Goat polyclonal antibody to C1D.
Applications:	ELISA, WB
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to Human C1D (C terminal).
Sequence:	C-SKNASKVANKGKSKS
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity).
Tissue Specificity:	Ubiquitous. Expressed at very high levels in the hippocampus, medulla oblongata, mammary gland, thyroid and salivary gland. Expressed at high levels in the fetal; lung, liver and kidney. Expressed at low levels in skeletal muscle, appendix, heart, lung and colon.
Sequence Similarities:	Belongs to the C1D family.
Post-Translational Modification:	Phosphorylated by PRKDC.
Cellular Location:	Nucleus. Cytoplasm. Nucleus > Nucleolus. EXOSC10 is required for nucleolar localization (PubMed:17412707). Colocalizes with TSNAX in the nucleus (PubMed:11801738).
Database Links:	Entrez Gene: 10438?Human Omim: 606997?Human SwissProt: Q13901?Human Unigene: 602900?Human Unigene: 697447?Human
Synonyms:	1110036E10Rik Antibody AI875855 Antibody C1D Antibody C1D DNA binding protein Antibody C1D_HUMAN Antibody hC1D Antibody LRP1 Antibody MGC12261 Antibody MGC14659 Antibody MGC188504 Antibody Nuclear DNA binding protein Antibody Nuclear nucleic acid binding protein C1D Antibody Nuclear nucleic acid-binding protein C1D Antibody rCG23324 Antibody RGD1560600 Antibody Small unique nuclear receptor corepressor Antibody SUNCOR Antibody
Information:	Target information shown above is from the UniProt Consortium.