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Anti-C14orf166 Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-C14orf166 Antibody

商品詳情參考文獻(xiàn) 相關(guān)資料

Overview

Name:	Anti-C14orf166 Antibody See all C14orf166 primary antibodies
Description:	Rabbit polyclonal antibody to C14orf166.
Applications:	WB
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human
Immunogen:	Recombinant protein of human C14orf166.
Protein Length:	244
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. In case of infection by influenza virus A, is involved in viral replication. Component of the tRNA-splicing ligase complex and is required for tRNA ligation (PubMed:24870230). May be required for RNA transport (PubMed:24608264).
Tissue Specificity:	Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in *** brain, *** lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors.
Sequence Similarities:	Belongs to the UPF0568 family.
Cellular Location:	Nucleus. Cytoplasm > Cytosol. Cytoplasm > Perinuclear region. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. May localize at the centrosome during mitosis. Shuttles between the cytosol and the nucleus: enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low (PubMed:24608264).
Database Links:	Entrez Gene: 51637?Human Omim: 610858?Human SwissProt: Q9Y224?Human Unigene: 534457?Human
Synonyms:	C14orf166 Antibody CGI 99 Antibody CGI-99 Antibody CGI99 Antibody Chromosome 14 open reading frame 166 Antibody CLE Antibody CLE7 Antibody CN166_HUMAN Antibody Homeobox prox 1 Antibody LCRP369 Antibody RLL motif containing 1 Antibody RLLM1 Antibody UPF0568 protein C14orf166 Antibody
Information:	Target information shown above is from the UniProt Consortium.