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Anti-BSG / EMMPRIN (Q370) Antibody

品牌：Antibodies

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規(guī)格：50μl

貨期：

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Anti-BSG / EMMPRIN (Q370) Antibody

商品詳情參考文獻相關資料

Overview

Name:	Anti-BSG / EMMPRIN (Q370) Antibody See all BSG primary antibodies
Description:	Rabbit polyclonal antibody to BSG / EMMPRIN (Q370)
Specificity:	EMMPRIN (Q370) pAb detects endogenous levels of EMMPRIN protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 350-400 of Human EMMPRIN.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 42 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Target

Function:	Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
Tissue Specificity:	Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
Post-Translational Modification:	N-glycosylated.
Cellular Location:	Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In spermatozoa, localized on the principal piece of caput and in the middle piece during transit in the corpus and cauda epididymides (By similarity).
Database Links:	Entrez Gene: 682?Human Entrez Gene: 12215?Mouse Entrez Gene: 25246?Rat Omim: 109480?Human SwissProt: P35613?Human SwissProt: P18572?Mouse SwissProt: P26453?Rat Unigene: 501293?Human Unigene: 431532?Mouse Unigene: 726?Mouse Unigene: 2269?Rat
Synonyms:	5A11 antigen Antibody 5F7 Antibody Basigin Antibody Basigin (Ok blood group) Antibody BASI_HUMAN Antibody Blood brain barrier HT7 antigen Antibody Bsg Antibody CD 147 Antibody CD147 Antibody CD147 antigen Antibody Collagenase stimulatory factor Antibody EMMPRIN Antibody Extracellular matrix metalloproteinase inducer Antibody Leukocyte activation antigen M6 Antibody M 6 Antibody M6 Antibody M6 leukocyte activation antigen Antibody Neurothelin Antibody OK Antibody OK blood group Antibody OK blood group antigen Antibody TCSF Antibody Tumor cell derived collagenase stimulatory factor Antibody Tumor cell-derived collagenase stimulatory factor Antibody
Information:	Target information shown above is from the UniProt Consortium.