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Anti-BRAP Antibody

品牌：Antibodies

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規(guī)格：50μl

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Anti-BRAP Antibody

商品詳情參考文獻相關資料

Name:	Anti-BRAP Antibody See all BRAP primary antibodies
Description:	Mouse monoclonal antibody to BRAP
Specificity:	This antibody detects endogenous levels of BRAP and does not cross-react with related proteins.
Applications:	WB
Dilutions:	Western blotting: 1:1000
Reactivity:	Human
Immunogen:	Purified recombinant human BRAP protein fragments expressed in E.coli.
Host:	Mouse
Clonality:	Monoclonal
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	Affinity purified
Formulation:	Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage:	store at -20?C

Function:	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Tissue Specificity:	Expressed in breast epithelial cell lines.
Cellular Location:	Cytoplasm.
Database Links:	Entrez Gene: 8315?Human Omim: 604986?Human SwissProt: Q7Z569?Human
Synonyms:	3010002G07Rik Antibody BRAP Antibody BRAP2 Antibody BRCA1 associated protein Antibody EC 6.3.2. Antibody Galectin 2 binding protein Antibody IMP Antibody Impedes mitogenic signal propagation Antibody Renal carcinoma antigen NY REN 63 Antibody RING finger protein 52 Antibody RNF52 Antibody zgc:92894 Antibody
Information:	Target information shown above is from the UniProt Consortium.